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. Author manuscript; available in PMC: 2016 Jan 8.
Published in final edited form as: Front Biosci (Landmark Ed). 2016 Jan 1;21:397–409. doi: 10.2741/4396

Figure 3.

Figure 3

Echocardiography evaluation of right ventricle and pulmonary arteries of wild type and TLR4−/− mice. A). Representative WT mouse B-mode long axis of RV and LV. B). M-mode tracing of the RV captured in a line perpendicular to the long axis of the chamber passing through the tip of the left posterior papillary muscle (left). RVEDD and RVFW thickness at end-diastole (left lines) and systole (right lines). C). In vivo Echo M-mode RV measurements for parasternal long axis of the WT and TLR4−/− mice. D). Representative Doppler echocardiography tracings of pulmonary artery blood flow velocity in the main pulmonary artery. E). Illustration of the measurement of pulmonary arterial acceleration time (PAAT). The PAAT was determined from the start to the peak of the flow signal of three consecutive beats. Two areas were measured for each mouse. F). PAAT in WT (n=4 mice) and TLR4−/− mice (n=3, *p<0.05).