Table II.
Compound | Parameter value listed | Updated parameter value |
---|---|---|
% dose excreted as unchanged drug in urine | ||
Memantine | 71 | 48 |
Pravastatin | 20 | 47 |
Ranitidine | 30 | 69 |
Rosuvastatin | 5 | 30 |
Solubility | ||
Atorvastatin | 0.0000204 mg/mL | 0.0204 mg/mL |
Diclofenac | 9 mg/mL | 0.14 mg/mL |
Administration route | ||
Enalaprilat | Oral | Intravenous |
Vancomycin | Oral | Intravenous |
Tiotropium bromide | Oral | Inhaled |