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editorial
. 2015 Oct 1;18(1):15–22. doi: 10.1208/s12248-015-9830-9

Table VI.

Example Data Showing the Importance of Determining the Last Time Point for Calculation of f 2

Both test and reference have reached 85% dissolution Any one of the reference or test product has reached 85% dissolution
Time (min) % Dissolved % Dissolved
Reference Test Reference Test
10 25 33 25 33
15 50 66 50 66
20 79 85 79 85
30 83 87 83 87
45 88 89 88 89
f 2 53 (similar) 48 (not similar)