Table VII.

Similarities and Differences in Coefficient of Variation Criteria

Country	Coefficient of variation criteria
United States (14), Canada (19), South (28) Africa, Brazil (18)*	The percent coefficient of variation at the earlier time points should be not more than 20%, and at other time points should be not more than 10%. *For Brazil, the first 40% of time points are considered “earlier time points”
Europe (5), Australia (17), Russia (5), China (20), Mexico (25), Turkey (27)	The percent coefficient of variation at the first time point should be not more than 20%, and at other time points should be not more than 10%
South Korea (29)	The percent coefficient of variation should be not more than 15% at all time points
Thailand (26)	The percent coefficient of variation should be not more than 10% from second to last time points
Japan (6,22,24)	The absolute difference of mean is applied in the Japanese guidance