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TABLE 1.

A. phagocytophilum organisms in BALB/c mouse blood following homologous and heterologous challenge

Group no. Original isolate Challenge isolate 7 days PCH
14 days PCH
21 days PCH
No. of PCR-positive mice (n = 6) No. of organismsa No. of PCR-positive mice (n = 6) No. of organisms No. of PCR-positive mice (n = 6) No. of organisms
1 Dawson None 0 0 0 0 0 0
2 Dawson Dawson 6 3,944 ± 3,292 0 0 2 93 ± 144
3 Dawson Gaillard 6 2,380 ± 2,626 3 196 ± 258 0 0
4 None Dawson 6 11,893 ± 9,251 5 3,241 ± 6,723 6 5,150 ± 4,940
5 Gaillard None 0 0 0 0 0 0
6 Gaillard Gaillard 5 3,572 ± 5,083 3 213 ± 439 0 0
7 Gaillard Dawson 6 1,156 ± 672 4 62 ± 55 0 0
8 None Gaillard 6 62,563 ± 47,591 2 73 ± 150 5 6,409 ± 6,906
a

Average number of A. phagocytophilum organisms per 100 μl of whole blood ± standard deviations.