Table 1. Genotyping results of variant HABP2 G534E (rs7080536) in Ohio cohorts.
| Genotype | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| GG | GA | AA | Minor Allele Frequency (%) | p-value* | |||||
| Sample | Individuals | Count | Proportion (%) | Count | Proportion (%) | Count | Proportion (%) | ||
| Familial PTC | 179 | 168 | 93.9 | 11 | 6.1 | 0 | 0.0 | 3.1 | 0.32 |
| Group 1 (3+) | 103 | 97 | 94.2 | 6 | 5.8 | 0 | 0.0 | 2.9 | 0.46 |
| Group 2 (2) | 76 | 71 | 93.4 | 5 | 6.6 | 0 | 0.0 | 3.3 | 0.67 |
| Sporadic PTC | 1160 | 1067 | 92.0 | 91 | 7.8 | 2 | 0.17 | 4.1 | 0.24 |
| Controls | 1395 | 1274 | 91.3 | 121 | 8.7 | 0 | 0.0 | 4.3 | |
* Fisher's Exact test p-value, comparing genotype distributions with Controls