Skip to main content
. 2016 Jan 8;11(1):e0146521. doi: 10.1371/journal.pone.0146521

Fig 4. H. pylori induces aberrant DNA methylation in cells.

Fig 4

(A) Electrophoretic analysis of the promoter CpG islands of the indicated genes by bisulfite modification-PCR. (B) Methylation sites of the CpG islands at the indicated gene promoters. LDH, L-lactate dehydrogenase. DLD, Dihydrolipoamide dehydrogenase. RanGAP, Ran-specific GTPase-activating protein. CaM, Calmodulin. M, Molecular weight marker. 1, untreated SGC-7901 cells; 2, H. pylori-infected SGC-7901 cells; 3, cagA-overexpressing SGC-7901 cells. The arrows indicate abnormal methylation sites.