Table 1.

χ² Analysis: Effect of TCZ on MMP-9 Production by C28/I2 Chondrocytes.

Group	[TCZ]	60 min	4 hrs
1	200 ng/ml1	χ2=0.38; p = 0.54	χ2=9.6; p = 0.002*
2	400 ng/ml2	χ2=10.1; p = 0.001*	χ2=18.7; p = 1.5 × 10−5*
3	600 ng/ml3	χ2=3.96; p = 0.046*	χ2=17.6; p = 2.6 × 10−5*
4	800 ng/ml4	χ2=5.16; p = 0.02*	χ2=17.6; p = 2.6 × 10−5*

Ratio of [TCZ] to [rhIL-6]:

¹4:1

²8:1

³12:1

⁴16:1

^*p-value for significance was <0.05