TABLE 1.
Severity of malaria | Geometric mean no. of parasites/μla | Hemozoin concn (fg/pRBC)b | Estimated hemozoin concn in blood from children with malaria (μg/ml)c |
---|---|---|---|
Mild | 41,369 | 47 | 1.9 |
Severe | 275,005 | 47 | 12.9 |
Calculated from blood of children with mild (n = 17) and severe (n = 12) malaria (21).
Calculated from cultured parasites (10).
Determined by multiplying the concentration of hemozoin (in femtograms per pRBC) obtained from cultured parasites by the geometric mean number of parasites per microliter in children with mild and severe malaria.