Fig 9. Increased CCR5 expression in peripheral blood monocytes/macrophages of Tet-mev-1 mice.

(A) Activated monocytes/macrophages were identified as an F4/80⁺/CD11b⁺/Ly-6C^high cell fraction (P3) in male wild type (WT) and Tet-mev-1 mice that had been supplied with doxycycline-containing water and were subsequently fed a normal diet (ND) or high-fat/high-sucrose diet (HFHSD) for 4 months. (B) CCR5 expression in these cells was analyzed by measuring the intensities of APC fluorescence bound to anti-CCR5 antibodies using five to six mice per group. The asterisks indicate that the differences between the groups are statistically significant (*p < 0.01).