Table 1. Functional annotation of gene ontology using microarray data.
Mice / Diet | Fold change | Number of changed probes | GO accession number | GO term | Number of elected probes | p value |
---|---|---|---|---|---|---|
WT / ND vs Tet-mev-1 / ND | ≥ 10 | 10 | No hit | - | - | |
≥ 5 | 83 | No hit | - | - | ||
WT / HFHSD vs Tet-mev-1 / HFHSD | ≥ 10 | 16 | No hit | - | - | |
≥ 5 | 70 | No hit | - | - | ||
WT / ND vs WT / HFHSD | ≥ 10 | 69 | GO:0006629 | lipid metabolic process | 11 | 0.0331 |
≥ 5 | 217 | No hit | - | - | ||
Tet-mev-1 / ND vs Tet-mev-1 / HFHSD | ≥ 10 | 53 | No hit | - | - | |
≥ 5 | 208 | GO:0005576 | extracellular region | 34 | 6.28E-04 | |
GO:0008009 | chemokine activity | 6 | 0.0012 | |||
GO:0006952 GO:0002217 GO:0042829 | defense response | 16 | 0.0035 | |||
GO:0042379 | chemokine receptor binding | 6 | 0.0035 | |||
GO:0044421 | extracellular region part | 22 | 0.0036 | |||
GO:0002376 | immune system process | 20 | 0.0263 | |||
GO:0006955 | immune response | 12 | 0.0359 |
WT, wild type; ND, normal diet; HFHSD, high-fat/high-sucrose diet.