Table 4.
Univariate and multivariate analysis for clinical and radiographic predictors of local control for SBRT patients
| Clinical |
Radiographic |
|||||
|---|---|---|---|---|---|---|
| Univariate |
Multivariate |
Univariate |
Multivariate |
|||
| Variable | P value | HR (95% CI) | P value | P value | HR (95% CI) | P value |
| BED (≥80 Gy) | .053 | 0.140 (0.025-0.787) | .026 | .008 | 0.238 (0.038-1.514) | .13 |
| GTV (cm3) | .91 | 1.003 (0.990-1.016) | .651 | .707 | 1.003 (0.985-1.020) | .767 |
| Sex | .088 | - | - | .136 | - | - |
| Age | .083 | - | - | .094 | - | - |
| >5 metastatic lesions treated | .304 | - | - | .938 | - | - |
| Location of lesion | .397 | - | - | .788 | - | - |
| Total dose | .415 | 1.000 (1.000-1.001) | .829 | .079 | 1.000 (1.000-1.000) | .223 |
| Smoking history | .309 | - | - | .444 | - | - |
| Systemic therapy before radiation | .821 | - | - | .588 | - | - |
| Systemic therapy after radiation | .643 | - | - | .296 | - | - |
BED, biologic effective dose; CI, confidence interval; GTV, gross tumor volume; HR, hazard ratio.