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. Author manuscript; available in PMC: 2016 Feb 1.
Published in final edited form as: J Orthop Res. 2014 Oct 28;33(2):174–184. doi: 10.1002/jor.22749

Figure 3.

Figure 3

SDF-1β promotes BMSC-mediated new bone formation following direct tibial transplantation in irradiation-preconditioned animals. Representative 3-D reconstructions of μCT images 4 weeks post-transplantation (side, coronal, and transverse views; ROI: starting immediately beyond the epiphyseal plate and extending 2 mm distally by transaxial tracing for 112 cuts). (A) Vehicle-transplanted (right) tibiae. (B) Tet-Off-SDF-1β (−Dox), C) Tet-Off-SDF-1β (+Dox), and D) Tet-Off-EV BMSC-transplanted (left) tibiae at 1.32 × 107 cells/ml (n = 5/Tet-Off-SDF-1β (−Dox); n = 5/Tet-Off-SDF-1β (+Dox); n = 10/Tet-Off-EV).