Table 1. Baseline demographics and transplant characteristics.
| Characteristic | Number (%) N=215 | |
|---|---|---|
| Age, year, median (range) | 55.1 (21.7-72.1) | |
| Sex, N (%) | ||
| Female/male | 81 (37.7)/134 (62.3) | |
| Underlying disease, N (%) | ||
| Acute leukemia | 93 (43.3) | |
| Multiple myeloma | 58 (27.0) | |
| MDS | 44 (20.5) | |
| MPD* | 12 (5.5) | |
| Lymphoma/Chronic lymphocytic leukemia | 6 (2.8) | |
| Non-hematologic malignancy | 2 (0.9) | |
| Conditioning regimen, N (%) | ||
| Busulfan/Melphalan/Fludarabine | 163 (75.8) | |
| TBI/Thiotepa/Cyclophosphamide | 46 (21.4) | |
| Thiotepa/Melphalan/Clofarabine | 6 (2.8) | |
| Recipient CMV serostatus, N (%) | ||
| Negative | 89 (41.4) | |
| Positive | 126 (58.6) | |
| Donor type, N (%) | ||
| Matched related | 64 (29.8) | |
| Matched unrelated | 107 (49.8) | |
| Mismatched (related or unrelated) | 44 (20.4) | |
| Acute GVHD, N (%) | ||
| Grade 0 | 176 (81.9) | |
| Grade I | 18 (8.4) | |
| Grade II | 20 (9.3) | |
| Grade III | 1 (0.5) | |
| Grade IV | 0 (0.0) |
*
MPD: Chronic myelomonocytic leukemia 1 patient, essential thrombocytopenia 2 patients, myelofibrosis 7 patients, and polycythemia vera 2 patients.
Abbreviations: MDS, myelodysplastic syndrome; MPD, myeloproliferative disease; MM, multiple myeloma; TBI, total body irradiation; CMV, cytomegalovirus; GVHD, graft-versus-host disease