Table 1.
Serum levels of 23 pro- and anti-inflammatory cytokines and chemokines (x) and their correlation to ipsilateral forepaw withdrawal threshold (y) on day 1 after neural injury.
| cytokine | correlation | R2 | p-value |
|---|---|---|---|
| pro-inflammatory | |||
| IL-7 | y=0.74x+0.77 | 0.617 | 0.0015 |
| IL-12 | y=0.73x+1.78 | 0.572 | 0.0028 |
| IL-1α | y=0.57x+1.07 | 0.558 | 0.0033 |
| TNF-α | y=0.72x+1.18 | 0.523 | 0.0052 |
| VEGF | y=0.43x+1.04 | 0.485 | 0.0082 |
| IL-17 | y=0.43x+0.98 | 0.479 | 0.0087 |
| G-CSF | y=0.66x+1.14 | 0.456 | 0.0113 |
| IL-1β | y=0.72x+1.04 | 0.446 | 0.0126 |
| MIP-3α | y=0.37x+1.03 | 0.422 | 0.0162 |
| IFN-γ | y=0.56x+1.09 | 0.376 | 0.0258 |
| IL-2 | y=0.41x+1.02 | 0.345 | 0.0348 |
| IL-18 | y=0.58x+1.01 | 0.283 | 0.0613 |
| GM-CSF | y=0.89x+1.25 | 0.173 | 0.1574 |
| GRO/KC | y=0.71x+1.13 | 0.163 | 0.1707 |
| RANTES | y=0.12x+0.98 | 0.042 | 0.5031 |
|
anti-inflammatory | |||
| IL-13 | y=0.68x+1.04 | 0.496 | 0.0072 |
| IL-10 | y=0.42x+0.94 | 0.439 | 0.0137 |
| IL-5 | y=0.27x+0.99 | 0.415 | 0.0175 |
| IL-4 | y=0.50x+1.02 | 0.383 | 0.0241 |
| EPO | y=0.56x+1.00 | 0.344 | 0.0352 |
| MCP-1 | y=0.21x+1.01 | 0.182 | 0.1459 |
|
both pro- and anti-inflammatory | |||
| IL-6 | y=0.56x+1.09 | 0.356 | 0.0315 |
| M-CSF | y=0.21x+1.01 | 0.321 | 0.0434 |
Note: shaded cells indicate R2 greater than 0.5.