Skip to main content
. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Biomaterials. 2015 Dec 2;80:68–79. doi: 10.1016/j.biomaterials.2015.11.051

Fig. 2. Efficiency of oral delivery and biodistribution of GFP fused with different tags.

Fig. 2

Serum (A) and tissue (B) GFP levels in mice (N=6 per group) fed leaf materials expressing CTB-GFP, PTD-GFP and DCpep-GFP. Adult mice were orally fed with leaf materials from transgenic tobacco plants, with the amount adjusted to GFP expression levels, for three consecutive days. A control group (N=6) kept unfed. Blood samples were collected at 2 and 5 hours after last gavage at which, mice were sacrificed and tissue samples were collected for protein isolation. GFP concentration in serum and tissues were measured with ELISA. The data was shown as average ± SEM. Statistic significance was determined by a paired Student’s t test, and p value less than 0.05 were considered significant. * P<0.05, ** P<0.01, *** P<0.05 or P<0.01 (CTD, PTD and DCpep versus Naïve)