Table 2. Multivariable logistic regression of surgical treatment vs. non-surgical treatment, conditional on individual patient characteristics.
Variable | Odds ratio of having surgery | 95% CI | P |
---|---|---|---|
Age at diagnosis | |||
70 years | Reference | – | – |
Per year over 70 | 0.84 | 0.82-0.87 | <0.001* |
Tumour grade | |||
1 | Reference | – | – |
2 | 0.92 | 0.58-1.46 | 0.723 |
3 | 1.18 | 0.63-2.21 | 0.600 |
HER2 status | |||
Negative | Reference | – | – |
Positive/borderline | 1.71 | 0.95-3.07 | 0.075 |
Nodal status | |||
Negative | Reference | ||
Positive | 0.85 | 0.54-1.34 | 0.495 |
Tumour size | |||
<10 mm | Reference | – | – |
10-19.9 mm | 0.81 | 0.41-1.61 | 0.551 |
20-49.9 mm | 0.84 | 0.56-1.25 | 0.396 |
≥50 mm | 0.36 | 0.19-0.70 | 0.003* |
Mini-Mental State Examination (MMSE) score | |||
27-30 | Reference | – | – |
22-26 | 0.89 | 0.54-1.48 | 0.658 |
0-21 | 0.57 | 0.26-1.24 | 0.156 |
Activities of daily living (ADL) score | |||
Independent | Reference | – | – |
Dependent | 0.44 | 0.28-0.69 | <0.001* |
Charlson Comorbidity Index (CCI) score | |||
0 | Reference | – | – |
1 | 0.58 | 0.36-0.95 | 0.023* |
2 | 0.58 | 0.37-0.94 | 0.026* |
≥3 | 0.47 | 0.28-0.69 | <0.001* |
Odds ratio >1 indicates increased odds of receiving surgery. * indicates statistical significance at 5% level.