FIG. 2.

Anti-carrier IgG antibody responses in single serum samples of mice immunized as described before. Since mice were immunized with equal amounts of MenC in either conjugate, the final amount of carrier protein is slightly different in the groups receiving the CRM-MenC and those that received the N19-MenC, due to the slight difference in the sugar-to-protein ratios in the two constructs. Serum samples were collected before (pre) and after (post-1, -2, and -3) each immunization and tested individually to quantitate carrier-specific IgG antibody titers. Each point represents the mean antibody titer (± 1 SD) of each group at each time point.