Table 2.
MICs (μM±SE; N≥4; peptides dose range: 0–64 µM) after 24 h against two Gram+ and two Gram− bacterial strains (§ indicates data from [6] for comparison).
| Compound | S. aureus | S. epidermis | P. aeruginosa | E. coli |
|---|---|---|---|---|
| GA IV (§) | >64 | >64 | >64 | >64 |
| L1 | 32±0 | >64 | >64 | >64 |
| L4 | >64 | >64 | >64 | >64 |
| L1L8 | 32±0 | >64 | >64 | >64 |
| K2 (§) | 3±1.4 | 4.3±2 | >64 | 24±17.1 |
| K5 | 1±0 | 2±0 | >64 | 8±2 |
| K6 (§) | 3±1.7 | 4±0 | >64 | 16±0 |
| K9 (§) | 5.3±2.1 | 4.7±1.6 | 57±16 | 32±17.5 |
| K2K5 | 3.3±1.3 | 5±2.4 | 16±5 | 13.7±3.9 |
| K2K6 | 2.8±1.1 | 3.2±2.6 | 17.6±8.8 | 12.6±4.3 |
| K5K6 | 4±0 | 4±1 | 16±0 | 16±0 |
| K2K5K9 | 4.3±1.8 | 4±0.9 | 13.3±4.1 | 14.9±8.6 |
| K5U6 | 3.8±2.4 | 2.4±0.9 | >64 | >64 |
| K2K5K9U6 | 4±0 | 8±0 | 8±0 | 8±0 |
| L1K2 | 4.6±1.5 | 4.7±1.6 | >64 | 22.9±8.6 |
| L1K9 | 4.7±1.6 | 4.6±1.5 | >64 | 41.1±15.6 |