Table 3.
The proportion of TB patients with low, normal and high hematological profile before initiation and after completion of the intensive phase tuberculosis treatment at University of Gondar hospital, 2014
Parameters | Category | Before TB treatment | After TB treatment | Reference Intervals | P-Value |
---|---|---|---|---|---|
RBC | Low | 91 (54.2) | 92 (54.8) | 0.92 | |
Normal | 72 (42.9) | 69 (41.1) | M = 4.5-6.2 × 106/ μl | ||
F = 4.0 -5.5 × 106/μl | |||||
High | 5 (3) | 7 (4.2) | |||
WBC | Low | 24 (14.3) | 31 (18.5) | 0.262 | |
Normal | 115 (68.5) | 113 (67.3) | 4.0 – 10.0 × 103/μl | ||
High | 29 (17.3) | 24 (14.3) | |||
HCT | Low | 86 (51.2) | 122 (72.6) | 0.000* | |
Normal | 69 (41.1) | 42 (25.0) | M = 40 -52 % | ||
F =36 – 47 % | |||||
High | 13 (7.7) | 4 (2.4) | |||
HGB | Low | 92 (54.8) | 121 (72) | 0.000* | |
Normal | 76 (45.2) | 47 (28) | M = 13 – 18 g/dl | ||
F = 12–16 g/dl | |||||
High | 0 (0) | 0 (0) | |||
MCV | Low | 13 (7.7) | 10 (6) | 0.589 | |
normal | 129 (76.8) | 130 (77.4) | 80 – 100 fl | ||
high | 26 (15.5) | 28 (16.7) | |||
MCH | low | 37 (22) | 18 (10.7) | 0.000* | |
Normal | 96 (57.1) | 105 (62.5) | 27 – 32 pg | ||
High | 35 (20.8) | 45 (26.8) | |||
MCHC | low | 75 (44.6) | 163 (98.2) | 0.000* | |
normal | 90 (53.6) | 3 (1.8) | 31.5 – 36 g/dl | ||
RDW_CV | Normal | 118 (70.2) | 9 (5.4) | 11.5 - 14.5 % | 0.000* |
high | 50 (29.8) | 159 (94.6) | |||
PLT | low | 22 (13.1) | 25 (14.9) | 0.01* | |
normal | 113 (67.3) | 128 (76.2) | 150 - 450 × 103/μl | ||
High | 33 (19.6) | 15 (8.9) | |||
PDW | Normal | 157 (93.5) | 167 (99.4) | 10 -17 % | 0.000* |
high | 11 (6.5) | 1 (0.6) | |||
Lymphocyte | low | 4 (2.4) | 6 (3.6) | 1.000 | |
Normal | 160 (95.2) | 156 (92.9) | 1.5 - 4.5 × 103/μl | ||
high | 4 (2.4) | 6 (3.6) | |||
Mixed cell | Normal | 160 (95.2) | 165 (98.2) | 0.26 -1.3 × 103/μl | 0.960 |
high | 8 (4.8) | 3 (1.8) | |||
Neutrophil | Low | 13 (7.7) | 24 (14.3) | 0.233 | |
Normal | 136 (81) | 124 (73.8) | 2.0 – 7.0 × 103/μl | ||
High | 19 (11.3) | 20 (11.9) |
* = significant association. Hematological parameter values less than and greater than the reference intervals are categorized as low and high respectively