Table 1.
Worm recoveries from dogs treated with 4 monthly doses of Advantage Multi for Dogs with the last treatment being 28 days before being inoculated with L3 Dirofilaria immitis larvae from mosquitoes. Shown in the table are the dogs’ IDs and gender, ELISA OD value on Day 264 (152 days after inoculation with larvae), and the number of male, female, and total worms recovered from each dog
| Number of Worms Recovered | |||||
|---|---|---|---|---|---|
| Dog ID | Gender | ELISA OD Day 264 | Males | Females | Total |
| DOGS TREATED WITH ADVANTAGE MULTI® FOR DOGS | |||||
| 501 | Male | 0.055 | 0 | 0 | 0 |
| 701 | Male | 0.052 | 0 | 0 | 0 |
| 801 | Male | 0.054 | 0 | 0 | 0 |
| 601 | Male | 0.057 | 0 | 0 | 0 |
| 505 | Female | 0.060 | 0 | 0 | 0 |
| 705 | Female | 0.056 | 0 | 0 | 0 |
| 703 | Female | 0.054 | 0 | 0 | 0 |
| 704 | Female | 0.056 | 0 | 0 | 0 |
| Geometric mean: | 0.00 | 0.00 | 0.00 | ||
| NONTREATED CONTROL DOGS | |||||
| 502 | Male | 0.063 | 12 | 22 | 34 |
| 702 | Male | 0.055 | 7 | 18 | 25 |
| 306 | Male | 0.080* | 13 | 21 | 34 |
| 401 | Male | 0.055 | 14 | 17 | 31 |
| 504 | Female | 0.093* | 13 | 24 | 37 |
| 506 | Female | 0.090* | 20 | 21 | 41 |
| 503 | Female | 0.079* | 13 | 23 | 36 |
| 602 | Female | 0.090* | 21 | 15 | 36 |
| Geometric mean: | 13.47 | 19.90 | 33.94 | ||
*The asterisk next to the OD (Optical Density) indicates these dogs were considered antigen positive because the OD reading was >0.005 above the negative control reading of 0.067