Table 2.
Changes in other asthma medications post omalizumab therapy
| Duration >120 days | Baselinea | Follow-upb | p-valuec |
|---|---|---|---|
| N = 158 | N (%) | N (%) | |
| ICS | <0.001* | ||
| With ICS | 158 (100.0 %) | 138 (87.3 %) | |
| Without ICS | 0 (0.0 %) | 20 (12.7 %) | |
| ICS + LABA | <0.001* | ||
| With ICS + LABA | 157 (99.4 %) | 124 (78.5 %) | |
| Without ICS + LABA | 1 (0.6 %) | 34 (21.5 %) | |
| OCS | <0.001* | ||
| With OCS | 146 (92.4 %) | 91 (57.6 %) | |
| Without OCS | 12 (7.6 %) | 67 (42.4 %) | |
| SAMA | <0.001* | ||
| With SAMA | 49 (31.0 %) | 4 (2.5 %) | |
| Without SAMA | 109 (69.0 %) | 154 (97.5 %) | |
| LAMA | 0.027* | ||
| With LAMA | 27 (17.1 %) | 13 (8.2 %) | |
| Without LAMA | 131 (82.9 %) | 145 (91.8 %) |
aBaseline: 1 year before the index date
bFollow-up: 2 months before discontinuation (discontinuation of therapy was defined as a gap in therapy of 56 days)
cFisher’s exact test, *P < 0.05