TABLE 2.
| Immunization group |
P value for the following groupc:
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| PBS | NI-IgG | Indifferent MAb | PLY-7 | PLY-4 | PLY-5 | 2 MAbs | 3 MAbs | Anti-PLY IgG | |
| PBS | 0.0003 | 0.0198 | NS | <0.0001 | NS | 0.0002 | <0.0001 | <0.0001 | |
| NI-IgG | NS | ND | ND | ND | ND | ND | ND | 0.0001 | |
| Indifferent MAb | NS | ND | NS | 0.0048 | NS | 0.0288 | 0.0010 | ND | |
| PLY-7 | NS | ND | NS | ND | ND | ND | 0.0007 | ND | |
| PLY-4 | NS | ND | NS | ND | ND | NS | 0.0443 | 0.0032 | |
| PLY-5 | NS | ND | NS | ND | ND | ND | <0.0001 | ND | |
| 2 MAbs | 0.0033 | ND | NS | NS | NS | 0.0197 | NS | NS | |
| 3 MAbs | 0.0004 | ND | 0.0138 | 0.0407 | 0.0138 | 0.0033 | NS | NS | |
| Anti-PLY IgG | <0.0001 | <0.0001 | 0.0003 | 0.0003 | <0.0001 | <0.0001 | NS | NS | |
Differences in median survival times between groups of mice protected with the indicated antibody were analyzed by using the Mann-Whitney U test.
Differences in survival rates between groups of mice were analyzed by using the Fisher exact test.
2 MAbs: PLY-4 and PLY-7; 3 MAbs: PLY-4, PLY-7, and PLY-5. NS, not significant; ND, not determined.