Skip to main content
. Author manuscript; available in PMC: 2016 Jan 9.
Published in final edited form as: J Toxicol Environ Health B Crit Rev. 2015;18(0):121–212. doi: 10.1080/10937404.2015.1051611

FIGURE 8.

FIGURE 8

Novel method using hybrid markers to quantify MWCNT in tissues. a. Lung exposed to MWCNT. b. Transfer of lung tissue into C99 at room temperature. c. Lung digestion in C99. d. Lung solution centrifugation at 12,000 rpm for 10 minutes.

e. Supernatant removal. f. Novel method using hybrid markers. Marker adsorbtion onto MWCNT for 15 min. g. Extraction of adsorbed B(ghi)P on MWCNTs to acetonitrile. h. Filtration of B(Ghi)P in the MWCNT. i. HPLC analysis.

Limit of quantitation is 0.2 µg in MWCNT in rat lung.