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The effect of the knockdown of HYPDH and GO in Agxt KO mice on urinary oxalate (panel A) and glycolate (panel B) excretion. Wt baseline, open bars; Wt post siRNA, black bars. Agxt KO baseline, dotted bars; Agxt KO post siRNA, diagonal lines. ** P<0.01, *** P<0.001 between baseline and post siRNA treatment analyzed by paired t-test. Results presented are means ± SD.
