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Percentage of antibodies (y axis) made against the P. falciparum 3D7 AMA-1 ectodomain (D I+II+III) that bind to individual domain constructs. Most of the antibodies generated by D I+II+III were directed to epitopes present in the D I+II region (P < 0.00008). The 100% point is equivalent to the ELISA value of anti-D I+II+III antibody that bound to D I+II+III protein. Error bars represent the variation observed in triplicate wells in two experiments.
