. Author manuscript; available in PMC: 2016 Dec 1.

Published in final edited form as: Pain Med. 2015 Jul 14;16(12):2386–2396. doi: 10.1111/pme.12842

Table 4.

Sensitivity Analysis of Determinants of Pain Cessation Rate Multivariate Models^a

Multivariate Model Variation	ASI Score^a	Fear of Pain Score^a	Legitimate Preoperative Opioid Use	Self-Perceived Risk of Addiction^a	Preoperative Illicit Opioid Use	Preoperative Pain (Surgical Site)^a	Preoperative Pain (Non-Surgical Site)^a	AIC
Multivariate Model Variation	HR (95%CI); P-Value	HR (95%CI); P-Value	HR (95%CI); P-Value	HR (95%CI); P-Value	HR (95%CI); P-Value	HR (95%CI); P-Value	HR (95%CI); P-Value	AIC
Full model								329.654
Alternative Model Building Algorithms (Full Patient Set)
Backward Model Building Algorithm	1.89(1.23–2.90); 0.004	0.65(0.40–1.06); 0.08		0.62(0.39–0.97); 0.04	0.53(0.24–1.16); 0.1			329.654
Forward Model Building Algorithm	1.95(1.27–3.01); 0.003	0.60(0.36–0.99); 0.05	0.61(0.29–1.31); 0.2	0.61(0.38–0.96); 0.03	0.67(0.29–1.55); 0.3			329.942
Stepwise Model Building Algorithm	1.89(1.23–2.90); 0.004	0.65(0.40–1.06); 0.08		0.62(0.39–0.97); 0.04	0.53(0.24–1.16); 0.1			329.654
Final Model Plus Baseline Pain Severity at Surgical Site	1.83(1.21–2.76); 0.004	0.64(0.40–1.03); 0.07		0.60(0.38–0.95); 0.03		1.36(0.79–2.35); 0.3		341.991
Final Model Plus Baseline Pain Severity Other Than at Surgical Site	1.87(1.23–2.83); 0.003	0.65(0.40–1.04); 0.07		0.58(0.37–0.94); 0.03	0.48(0.22–1.06); 0.07		1.51(0.89–2.57); 0.1	340.889

Hazard ratios presented as the difference in hazard between the 25^th percentile and 75th percentile of that variable in the study population All models are stratified by surgery type; ASI= Anxiety Sensitivity Index.