Table 2. Spearman correlation coefficient of plasma inflammatory marker levels with age and lifestyle factors among control participants in the Nurses' Health Study (1990).
| Variable | MIC-1 | CRP | IL-6 | sTNFR-2 | Age | BMI | Physical activity | Pack-years of smoking | Alcohol consumption | Dietary AHEI score |
|---|---|---|---|---|---|---|---|---|---|---|
| MIC-1 | 1 | 0.19 a | 0.30 a | 0.38 a | 0.48 a | 0.04 | 0.02 | 0.13 a | -0.06 | 0.05 |
| CRP | 1 | 0.41 a | 0.38 a | 0.22 a | 0.38 a | -0.07 c | 0.10 a | -0.05 | -0.10 a | |
| IL-6 | 1 | 0.38 a | 0.21 a | 0.27 a | -0.06 | 0.05 | -0.12 b | -0.12 b | ||
| sTNFR-2 | 1 | 0.26 a | 0.24 a | -0.06 | 0.05 | -0.15 a | -0.10 b | |||
| Age | 1 | 0.07 | 0.06 | 0.09 c | 0.04 | 0.20 a | ||||
| BMI | 1 | -0.10 b | 0.02 | -0.10 b | -0.12b | |||||
| Physical activity | 1 | 0.01 | 0.17 a | 0.29 a | ||||||
| Pack-years of smoking | 1 | 0.28 a | 0.05 | |||||||
| Alcohol consumption | 1 | 0.21 a | ||||||||
| Dietary AHEI score | 1 |
Abbreviations: AHEI, Alternative Healthy Eating Index; BMI, body mass index; CRP, C-reactive protein; IL-6, interleukin-6; MIC-1, macrophage inhibitory cytokine-1; sTNFR-2, soluble tumor necrosis factor receptor 2.
a
P<0.001.
b
0.001≤P<0.01.
c
0.01≤P<0.05.