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Clinical isolate time course inhibition assays for tobramycin/D-met combinations. Graphs show optical density plotted over time during bacterial log growth phase. Tobramycin (at MIC) was combined with serial D-met dilutions (6400–100 μg/ml) and compared to clinical isolate growth. Studies were performed in triplicate. D-met did not significantly inhibit antimicrobial efficacy (p ≤ 0.05). Clinical isolates tested were: A) E. coli; B) S. aureus; and C) P. aeruginosa.
