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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Cancer. 2015 Oct 6;122(1):50–60. doi: 10.1002/cncr.29674

Table 3a. Overall survival analysis of year of diagnosis for patients treated and not treated with chemotherapy.

Period (years) N Hazard Ratio (95% CI) P-value Overall P-value
Overall population treated with chemotherapy 0.005

 1985-1990 1331 1 (Ref) -
 1991-1995 3666 1.027 (0.964 - 1.094) 0.404
 1996-2000 4327 1.002 (0.941 - 1.066) 0.956
 2001-2005 8393 0.959 (0.904 - 1.017) 0.160

Overall population not treated with chemotherapy <.001

 1985-1990 1860 1 (Ref) -
 1991-1995 3075 0.992 (0.936 - 1.052) 0.798
 1996-2000 4503 0.944 (0.894 - 0.997) 0.039
 2001-2005 7664 0.918 (0.872 - 0.967) 0.001

Hazard Ratio is calculated by the multivariable Cox proportional hazards model with year of diagnosis after adjusting for age, sex, race, stage, Medicare status, urban/rural, and radiation.