Table 1.

Top gene expression differences between APC and mature astrocytes. Genes are ranked by fold change in expression between APC and mature stages. The top and bottom 20 genes are listed. Genes with FPKM<10 in both APC and mature stages are excluded to highlight highly expressed genes that are more likely to be useful markers for APC or mature astrocytes. All genes have >2 fold enrichment in astrocytes over other cell types.

Top mature astrocyte genes				Top APC genes
Gene	Expression in fetal astrocytes	Expression in mature astrocytes	Fold change	Gene	Expression in fetal astrocytes	Expression in mature astrocytes	Fold change
AGXT2L1	0.1	238.6	1988.6	HIST1H2AI	57.9	0.1	578.9
S100A1	0.1	84.9	849.4	HIST1H3E	51.0	0.1	509.6
SLC14A1	0.1	29.3	334.6	HIST1H3B	176.6	0.6	292.1
TMEM176A	0.1	27.1	270.6	HIST1H1B	23.4	0.1	234.0
TMX2	0.1	25.9	259.1	PPDPF	26.4	0.2	119.3
HHATL	0.1	24.9	237.6	TPX2	22.0	0.2	93.9
PADI2	0.1	26.8	225.3	NUSAP1	27.4	0.3	90.4
TLR4	0.1	18.7	212.9	HIST1H2AC	39.0	0.5	76.8
HSD17B6	0.1	20.5	204.6	HIST2H2AC	68.9	1.3	53.2
CHI3L1	0.1	15.2	172.2	TNC	26.6	0.6	45.5
NUDT3	0.1	13.5	135.2	KIF15	17.2	0.5	32.7
FBXO2	0.1	10.8	115.1	HIST1H1A	45.9	1.5	30.7
NTSR2	0.1	10.8	107.5	HIST1H2BC	215.2	13.2	16.3
ALDH1L1	0.1	10.8	82.5	FABP5	23.9	1.5	15.5
ALDOC	4.8	371.0	77.6	DTYMK	10.3	0.7	14.8
SLC1A2	34.5	1987.9	57.6	RAB11B	10.9	0.8	13.5
RYR3	0.3	16.0	55.0	HES6	21.6	2.1	10.3
GABRA2	0.9	46.1	51.2	LRIG3	13.3	1.4	9.6
CPE	16.0	657.2	41.0	E2F5	10.1	1.4	7.2
GLUL	21.0	826.9	39.4	MPPED2	16.0	2.3	7.0