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Schematic of structural elements for a bubble microfluidics device. A hydrophilic substrate is etched away to leave small, ≈10- to 50-μm protrusions. Hydrophobic patches with a diameter of ≈10–100 μm (e.g., gold or Teflon) are then deposited next to the protrusions to accommodate the microbubbles and form a doublet.
