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Cooperativity between Ahr and RORγt in the Il22 transcriptional regulation. RORγt and Ahr may act synergistically to enhance the Il22 transcription, and this synergy may result from multiple molecular interactions. The interaction between Ahr and RORγt is depicted at the Il22 promoter. Similar synergy could be present at the intron 1 of the Il22, where AhRE and RORE cluster.
