TABLE 1.
Human Subject Demographics
| Young NonSmokers | Young Smokers | Older Nonsmokers | Older Smokers | P Value | |
|---|---|---|---|---|---|
| Age (years) | 25 ± 1 a | 27 ± 1a | 57 ± 2b | 57 ± 4b | .0001 |
| Gender (M/F) | 1/2 | 2/1 | 2/1 | 3/0 | – |
| Pack years | N/A | 4 ± 0.4a | N/A | 38 ± 6b | .014 |
| FEV1 (liter) | 3.7 ± 0.2 | 3.8 ± 0.3 | 3.2 ± 0.7 | 3.5 ± 0.3 | ns |
| % predicted FEV1 | 95 ± 6 | 94 ± 6 | 95 ± 5 | 97 ± 12 | ns |
| FVC (liter) | 4.7 ± 0.6 | 4.5 ± 0.3 | 4.9 ± 0.9 | 5.0 ± 0.1 | ns |
| % predicted FVC | 101 ± 5 | 91 ± 6 | 112 ± 7 | 108 ± 7 | ns |
| FEV1/FVC | 0.80 ± 0.05a | 0.86 ± 0.02a | 0.66 ± 0.03b | 0.70 ± 0.05b | .024 |
Data are expressed as the mean ± SD and groups that differ significantly (P < .05) are delineated by different letters.
N/A: not applicable