Fig. 5.

Effect of previous treatment of C3H10T1/2 stem cells in cell culture on their capacity to generate adipose tissue when s.c. implanted into athymic mice. C3H10T1/2 stem cells were treated with or without 50 ng/ml BMP4 until near confluency and implanted into athymic mice. Later (4 wk), the fat pads derived from the implanted cells were analyzed with hematoxylin/eosin staining and photographed. The 3T3-F442A preadipocytes serve as a positive control, and the development of adipose tissue from these implanted cells were compared to endogeneous epididymal fat pads.