Table 2.
Demographic and risk factor variables for ischemic stroke (IS) patients and control subjects.
| Characteristics | Controls (N = 250) n (%) | Ischemic stroke (N = 250) n (%) | Crude OR [95% CI], p value | *Adjusted OR [95% CI], p value |
|---|---|---|---|---|
| Age in years (Mean + S.D) | 52.83 ± 12.59 | 50.97 ± 12.70 | Matched | |
| Male/Female, n | 203/47 | 203/47 | ||
| LVD | - | 107 (42.8) | ||
| SVD | - | 83 (33.2) | ||
| CE | - | 26 (10.4) | ||
| ODE | - | 22 (8.8) | ||
| UDE | - | 12 (4.8) | ||
| NIHSS at admission (Mean + S.D) | - | 12.55 ± 13.42 | ||
| BI score at discharge (Mean + S.D) | - | 63.56 ± 16.69 | ||
| BI score at 6 months (Mean + S.D) | - | 85.51 ± 15.26 | ||
| mRS score at discharge (Mean + S.D) | - | 3.06 ± 1.05 | ||
| mRS score at 6 months (Mean + S.D) | - | 1.3 ± 1.16 | ||
| Hypertension | 42 (16.8) | 146 (58.4) | 8.4 [4.8 to 14.6],<0.0001 | 6.2 [3.2 to 12], < 0.0001 |
| Diabetes | 26 (10.4) | 79 (31.6) | 3.5 [2.1 to 5.7], < 0.0001 | 2.1 [1.1 to 4.2],0.02 |
| Dyslipidemia | 14(5.6) | 57(22.8) | 5.2 [2.6 to10.4], < 0.0001 | 2.4 [1.0 to 5.7],0.04 |
| Smoking | 67 (26.8) | 97 (38.8) | 1.7 [1.1 to 2.5],0.005 | 1.1 [0.6to1.9],0.69 |
| Alcohol | 56 (22.4) | 81 (32.4) | 1.8 [1.1 to 2.8],0.008 | 1.8 [0.9 to 3.5],0.05 |
| Myocardial Infarction | 4 (1.6) | 17 (6.8) | 5.3 [1.5 to 18.3],0.008 | 1.8 [0.4 to 7.1],0.36 |
| Migraine with Aura | 8 (3.2) | 10 (4) | 1.2 [0.4 to 3.1],0.63 | 1.6 [0.4 to 5.8],0.40 |
| Migraine without Aura | 4 (1.6) | 5 (2) | 1.2 [0.3 to 4.6],0.33 | 1.3 [0.1 to 10.9],0.78 |
| Low Socioeconomic Status | 14 (5.6) | 66 (26.4) | 5.0 [2.7 to 9.0], < 0.0001 | 7.5 [3.0 to18.2],<0.0001 |
| High BMI | 89 (35.6) | 77 (30.8) | 0.7 [0.4 to 1.0],0.11 | 0.8 [0.4 to1.4],0.50 |
| Sedentary Life Style | 106 (42.4) | 127 (50.8) | 1.4 [1.0 to 2.1],0.04 | 1.1 [0.6 to1.9],0.6 |
| Physical activity | 136 (54.4) | 107 (42.8) | 0.6 [0.4 to 0.8], 0.009 | 0.7 [0.4 to 1.3],0.36 |
| Family history of stroke | 9 (3.6) | 32 (12.8) | 3.5 [1.6 to 7.4],0.001 | 6.8 [2.2 to 20.9],0.001 |
| Family history of diabetes | 28 (11.2) | 48 (19.2) | 1.8 [1.1 to 3.1],0.015 | 3.1 [1.4 to 6.9],0.004 |
| Family history of hypertension | 34 (13.6) | 61 (24.4) | 2.0 [1.2 to 3.1],0.003 | 1.8 [0.9 to 3.4],0.06 |
| Family history of heart Attack | 14 (5.6) | 19 (7.6) | 1.4 [0.6 to 3.1],0.33 | 1.7[0.5 to 5.9],0.38 |
Conditional Logistic Regression Analysis.
*Adjusted variables include Hypertension, Diabetes, Dyslipidemia, Smoking, Family History of stroke, Alcohol, Sedentary Life Style and Low socioeconomic status.
Abbreviations: BMI- Body Mass Index; OR- Odds Ratio; CI- Confidence Interval; SD- Standard Deviation;LVD-Large Vessel Disease;SVD-Small Vessel disease;CE-Cardioembolic;ODE-Other determined etiology; UDE-Undetermined etiology.