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. 2016 Jan 11;9:494. doi: 10.3389/fnins.2015.00494

Figure 2.

Figure 2

Retroviral knockout of DCX abolishes DCX expression in vivo but does not affect cell survival at 7 dpi. (A) Representative image and quantification showing the survival ratio of infected NPCs is the same in WT and floxed DCX (DCXflox) mice at 7 dpi. (B) Knockout of DCX was confirmed by no detectable GFP and DCX co-labeled cells in DCXflox mice (arrows = GFP+DCX+ co-labeled cells, arrowhead = GFP+ DCX−). (C) Proportion of GFP-Cre NPCs expressing the immature marker NeuroD1 is similar between WT and DCXflox mice. N = 3 mice per genotype with the total number of cells analyzed in (B) 113 WT cells and 111 KO cells; (C) 164 WT cells and 135 KO cells. Scale bars = 10 μm.