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. 2016 Jan 11;6:416. doi: 10.3389/fphys.2015.00416

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Copyright © 2016 Iso, Moriuchi, Sagari, Kitajima, Iso, Tanaka, Kikuchi, Tabira and Higashi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The data analysis using integral mode. The red curve represents the sham NIRS waveform in one case. This waveform was created by averaging the data measured over 3 cycles in a block design. Linear fitting was applied to the data between pre-task (blue arrow) and post-task (green arrow) periods. The thick black arrow above the red curve indicates the task period, and the thin arrow shows the rest period. The vertical axis represents oxy-Hb concentration (mMmm), and the horizontal axis represents the time course of 1 cycle. The mean value of oxy-Hb measured between 5 and 20 s during the task (15 s, shaded gray area in averaged graph) was calculated.