Table 3.
Characteristics of MRSA isolates contained murA mutations.
| Types of mutation | Strain No. | Mutations in murA∗ | Fosfomycin MIC range (mg/L) | fosB gene |
|---|---|---|---|---|
| TypeAmurA | 1 | T125A (Truncated to 41 aa) | 1024 | Negative |
| TypeImurA | 1 | G193C (Val 65 Leu) | 2 | Negative |
| TypeIImurA | 29 | G770A (Gly 257 Asp) | 2 ~ >1024 | Negative |
| TypeIIImurA | 2 | C834A (Asp 278 Glu) | 1 ~ 2 | Negative |
| TypeIVmurA | 7 | A873T (Glu 291 Asp) | 1 ~ 2 | Negative |
| TypeVmurA | 1 | A1085G (Gln 362 Arg) | 2 | Negative |
| TypeVImurA | 5 | CG1187-1188AT (Thr 396 Asn) | 1 ~ 2 | Negative |
∗Deduced amino acid substitutions or sequence variations are shown in brackets.