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. 2016 Jan 10;8(1):4–12. doi: 10.4253/wjge.v8.i1.4

Table 2.

Advantages and disadvantages of available bowel preparations

Prep Advantages Disadvantages
4 L PEG Effective Poor taste
Safe in most populations Very high volumes
Poorly tolerated by patients
2 L PEG Effective Poor taste
Safe in most populations High volumes
High cost
MiraLAX Well tolerated by patients Not as effective as prescription PEG preparations
Available over the counter Rare reports of hyponatremia
Existing studies indicate it is safe
Sodium phosphate Available as oral tab Inappropriate for use in patients with renal disease, volume depletion, heart or liver failure, or who are taking ACEi or NSAIDs
Well tolerated by patients Risk of acute phosphate nephropathy and subsequent chronic kidney disease
Sodium picosulfate Cost
Well tolerated by patients Not as effective as PEG or OSS
OSS Small volumes to be ingested Inappropriate for patients with heart failure, renal insufficiency, end stage liver disease, or baseline electrolyte abnormalities
Pleasant taste High cost
Well tolerated by patients High cost
Highly effective Not as well studied
Available as oral tab

PEG: Preparation of polyethylene glycol; ACEi: Angiotensin converting enzyme inhibitors; NSAIDs: Nonsteroidal anti-inflammatory drugs; OSS: Oral sulfate solution.