Figure 4.
Inflammation. (a) Levels of Cox-2 mRNA expression in islets after 24 hours in culture at 150, 300, and 600 IEQ/cm2 under normoxic (PO2 160 mmHg) and hypoxic (PO2 15 mmHg) conditions. (b) Levels of Ho-1 mRNA expression after 24 hours in culture under the specified conditions. (c) IL-6 secretion was measured in islet medium after 24 hours in culture under the specified conditions. α p < 0.05 compared to the control, ααα p < 0.001 compared to 150 IEQ/cm2 under normoxic conditions, # p < 0.05 compared to 150 IEQ/cm2 under normoxic conditions, and & p < 0.05 and &&& p < 0.001 compared to 150 IEQ/cm2 under hypoxic conditions.