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Hepatotoxicity of APAP. APAP: acetaminophen; SULT: sulfotransferase; UGT: glucuronosyltransferase; CYPs: P450 cytochromes; APAP-S: APAP-sulfonate; APAP-G: APAP-glucuronide; NAPQI: N-acetyl-p-benzoquinone imine; GST: glutathione S-transferase; GSH: glutathione; ROS: reactive oxygen species.
