Figure 4. The effect of short-term oral exposure to various doses of CdCl₂ on the development of chemically-induced colitis in murine models.

(A) The change in body weight over the course of the DSS experiment. (B) The change in body weight recorded over the course of the DSS experiment and after replacement with tap water. Data are quoted as the mean ± SEM, n = 8 mice per condition. (C) The change in body weight recorded over the course of the TNBS experiment. (D) Macroscopic evaluation of colonic inflammation (the Wallace score); *p < 0.05, **p < 0.01, *0.05 < p < 0.1, compared with C2 (the colitis control).