Table 1. Levels of angiogenic-related proteins in different brain regions of serum-IGF-I-deficient (LID) mice.
VEGFR1 | VEGFR2 | CD31 | Tie-2 | Ang-1 | Ang-2 | VEGF | HIF-1α | |
---|---|---|---|---|---|---|---|---|
Cortex | 54 ± 22 | 86 ± 16 | 170 ± 51 | 81 ± 23 | 71 ± 8 | 107 ± 17 | 146 ± 17 | 89 ± 15 |
Cerebellum | 132 ± 38 | 120 ± 23 | 107 ± 23 | 90 ± 41 | 101 ± 21 | 94 ± 12 | 77 ± 6 | 101 ± 15 |
Hippocampus | 133 ± 38 | 94 ± 19 | 108 ± 23 | 143 ± 50 | 62 ± 15 | 103 ± 17 | 65 ± 17 | 95 ± 19 |
Values are expressed as percent ± SEM of levels found in control littermates. No significant differences were found for any of the proteins evaluated.