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. Author manuscript; available in PMC: 2016 Jan 11.
Published in final edited form as: Drug Metab Pharmacokinet. 2010 Oct 22;26(1):3–14. doi: 10.2133/dmpk.dmpk-10-rv-062

Table 11.

Rodent carcinogenic responses not likely to apply to humans.

Tumor site Illustrative chemical agents
Male rat kidney d-Limonene, unleaded gasoline
Male bladder Saccharin, nitrilotriacetic acid
Rat thyroid Goitrogens, some alkylcarbamates, fungicides
Forestomach Butylated hydroxyanisole, propionic acid, ethyl acrylate
Mouse liver Barbiturates, peroxisome proliferators