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. Author manuscript; available in PMC: 2016 Jan 11.
Published in final edited form as: Drug Metab Pharmacokinet. 2010 Oct 22;26(1):3–14. doi: 10.2133/dmpk.dmpk-10-rv-062

Table 2.

Contexts of drug toxicity.4)

Type Example
On-target (mechanism-based) Statins
Hypersensitivity and immunological Penicillins
Off-target Terfenadine
Biological activation Acetaminophen
Idiosyncratic Halothane