Table 7.

Drugs withdrawn for hepatotoxicity (U. S.).³⁵⁾

Drug	Date	Dose (mg/day)	Reactive products	Reference
Cincophen	1930	300	No
Iproniazid	1959	25–150	Yes	36)
Pipamazine	1969	15	No
Fenclozic acid	1970	300	Yes	37)
Oxyphenisatin	1973	50	No
Nialamide	1974	200	Yes	38)
Tienilic acid	1980	250–500	Yes	20)
Benoxaprofen	1982	300–600	Yes	39)
Nomifensine	1986	125	Yes	40)
Chlormezanone	1996	600	No
Bromfenac	1998	25–50	Yes
Troglitazone	2000	400	Yes	41)
Nefazodone	2004	200	Yes	42)
Pemoline	2005	38–110	No
			9/14 = 64%