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KAR or mGluR antagonists applied alone do not affect MF-LTP. (A, B) The GluK1 antagonists ACET (A: 0.1 nmol, i.h.; n = 5) or UBP161 (B, 1 nmol, i.h.; n = 5) fail to block MF-LTP. (C–F) The broad spectrum mGluR antagonist MCPG (C, 5 nmol, i.h.; n = 5), the mGlu5 receptor antagonist, MPEP (D, 1 nmol, i.h.; n = 4), the mGlu1 receptor antagonist LY367385 (E, 1 nmol, i.h.; n = 4) or the combination of LY367385 and MPEP (F, 1 and 1 nmol, i.h.; n = 4) does not block MF-LTP.
