Table 1. Effects of Naspm, ‘Pore Dead' GluA1-Q582E and miSAP97 Administered into the Core or the Shell on the Reinstatement of Sucrose Seeking.
| Treatment | N | Region administered | Reinstatement: active lever responding | Statistics |
|---|---|---|---|---|
| Saline | 5 | Core | 85.80±14.10 | t8=3.327, p<0.0104 |
| Naspm | 5 | Core | 28.60±9.826 | |
| Saline | 8 | Shell | 77.5±13.19 | t14=0.2291, p<0.8221 |
| Naspm | 8 | Shell | 81.25±9.689 | |
| HSV eGFP | 6 | Core | 77.67±16.64 | t10=0.4970, p<0.6299 |
| HSV GluA1-Q582E | 6 | Core | 89.83±17.96 | |
| HSV eGFP | 6 | Shell | 117.0±24.46 | t9=0.2370, p<0.8180 |
| HSV GluA1-Q582E | 5 | Shell | 125.2±23.93 | |
| HSV eGFP | 6 | Shell | 117.0±36.88 | t10=0.7485, p<0.4714 |
| HSV miSAP97 | 6 | Shell | 158.0±40.5 |
The active lever responding is expressed as mean±SEM. Note that intra-core Napsm significantly decreased sucrose seeking relative to control.