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This is an Open Access article distributed under the terms of the Creative
Commons Attribution License, which permits unrestricted use, distribution, and
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cited.
Fig. 1. : biological effects of the Trypanosoma cruzi strain
Berenice-62 infection in H9c2 cellular survival. Cells were grown and infected
with the parasite and the initial 48 h after parasitic infection were
investigated. A: infected cells were analysedvia fluorescence
microscopy; the nuclear material was labelled with DAPI (Bar = 50 μm and 100
μm). The representative rates of infected and uninfected cells are demonstrated
in the circle; B: cellular viability assays after T. cruzi
cellular infection; C: cellular and molecular analyses of the effect of the
PTEN inhibitor (SF1670) in H9c2 cells. Cellular viability was measured by the
formazan production and plotted in graphs. The western blot analyses
demonstrated the effect of the drug in AKT phosphorylation. The presented
values are the average from three independent experiments and the error bars
represent the standard deviation of the mean. One-way analysis of variance
testing showed significant differences between the control and cell samples and
the significance level was set at p < 0.05 (***).